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| Second Basemen Single-Season Games Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Games | IP | Year | Career Leaderboard |
| 1. | Todd Maher | 162 | 1441.0 | 2004 | |
| Albert Estrada | 162 | 1448.7 | 2002 | ||
| William Maxon | 162 | 1433.0 | 2001 | ||
| 4. | Joe Berard | 161 | 1444.3 | 2013 | |
| Gary Crawford | 161 | 1445.7 | 2001 | ||
| Danny Rayborn | 161 | 1435.3 | 2000 | ||
| 7. | Antonio Ramos | 160 | 1416.7 | 2001 | |
| William Maxon | 160 | 1439.3 | 2000 | ||
| Brian Marshall * | 160 | 1426.3 | 2000 | ||
| 10. | Todd Maher | 159 | 1366.3 | 2003 | |
| 11. | Tamajirou Kakuzo | 158 | 1346.0 | 2029 | |
| Brian Marshall * | 158 | 1407.0 | 2001 | ||
| 13. | Tony Luna | 157 | 1358.3 | 2017 | |
| Eduardo Ulibarri | 157 | 1364.0 | 2014 | ||
| Howard Luther | 157 | 1272.7 | 2006 | ||
| Danny Rayborn | 157 | 1321.7 | 2005 | ||
| Danny Rayborn | 157 | 1318.3 | 2004 | ||
| Frederick Traynor | 157 | 1335.0 | 2001 | ||
| James Dickson | 157 | 1349.0 | 2000 | ||
| 20. | Lester Griffey | 156 | 1304.7 | 2023 | |
| Ernest Meleschi | 156 | 1319.0 | 2009 | ||
| Seamus O'Dule * | 156 | 1351.7 | 2004 | ||
| Danny Rayborn | 156 | 1313.3 | 2003 | ||
| Joel Camacho | 156 | 1380.0 | 2001 | ||
| 25. | Blinky Crouch | 155 | 1290.3 | 2025 | |
| Seamus O'Dule * | 155 | 1342.0 | 2010 | ||
| Ernest Meleschi | 155 | 1313.3 | 2010 | ||
| Lane Commons * | 155 | 1321.7 | 2007 | ||
| Josephus Thomas | 155 | 1399.0 | 2006 | ||
| Adam Anderson | 155 | 1304.7 | 2006 | ||
| Zachary Matthews * | 155 | 1320.3 | 2003 | ||
| Joel Camacho | 155 | 1312.3 | 2002 | ||
| Frederick Traynor | 155 | 1292.7 | 2002 | ||
| Matthew Dismukes | 155 | 1310.3 | 2001 | ||
| Zachary Matthews * | 155 | 1361.7 | 2000 | ||
| Antonio Ramos | 155 | 1344.7 | 2000 | ||
| Joel Camacho | 155 | 1338.0 | 2000 | ||
| Hector Rodriguez | 155 | 1218.3 | 2000 | ||
| 39. | Jack Hesse | 154 | 1354.7 | 2029 | |
| Tamajirou Kakuzo | 154 | 1267.7 | 2026 | ||
| Jeff Arnette | 154 | 1273.3 | 2024 | ||
| Anthony Godwin | 154 | 1338.3 | 2021 | ||
| John Carsswell | 154 | 1312.0 | 2017 | ||
| Bobby Whittaker | 154 | 1297.7 | 2016 | ||
| Bobby Whittaker | 154 | 1344.0 | 2015 | ||
| Joe Berard | 154 | 1401.0 | 2012 | ||
| Adam Anderson | 154 | 1306.0 | 2010 | ||
| Lynn Labrecque | 154 | 1285.7 | 2009 | ||
| Ludwig Claus | 154 | 1213.0 | 2009 | ||
| Danny Rayborn | 154 | 1326.7 | 2007 | ||
| Danny Rayborn | 154 | 1356.7 | 2006 | ||
| Antonio Ramos | 154 | 1258.0 | 2005 | ||
| Brian Marshall * | 154 | 1327.3 | 2004 | ||
| Steven Wynn | 154 | 1285.0 | 2003 | ||
| Zachary Matthews * | 154 | 1288.3 | 2002 | ||
| Brian Marshall * | 154 | 1250.3 | 2002 | ||
| Todd Maher | 154 | 1320.3 | 2001 | ||
| 58. | Jack Hesse | 153 | 1345.0 | 2028 | |
| Fernando Selso | 153 | 1282.7 | 2028 | ||
| Blinky Crouch | 153 | 1275.3 | 2026 | ||
| Matthew Wolf | 153 | 1321.0 | 2025 | ||
| Jeff Arnette | 153 | 1310.3 | 2023 | ||
| Tamajirou Kakuzo | 153 | 1331.3 | 2017 | ||
| Mason Highsmith | 153 | 1329.3 | 2015 | ||
| Brian Marshall * | 153 | 1356.0 | 2012 | ||
| Lane Commons * | 153 | 1350.3 | 2008 | ||
| Howard Luther | 153 | 1313.7 | 2008 | ||
| Howard Luther | 153 | 1291.0 | 2007 | ||
| Brian Marshall * | 153 | 1319.3 | 2005 | ||
| Joel Camacho | 153 | 1288.3 | 2005 | ||
| Zachary Matthews * | 153 | 1359.0 | 2001 | ||
| James Dickson | 153 | 1341.0 | 2001 | ||
| Jose Abdullah | 153 | 1285.3 | 2000 | ||
| 74. | Blinky Crouch | 152 | 1353.3 | 2027 | |
| Fernando Selso | 152 | 1294.3 | 2027 | ||
| Joseph Flores | 152 | 1281.0 | 2027 | ||
| Jade Sanchez | 152 | 1313.3 | 2026 | ||
| Tamajirou Kakuzo | 152 | 1253.0 | 2025 | ||
| Vin Koenig | 152 | 1332.0 | 2022 | ||
| Seamus O'Dule * | 152 | 1315.3 | 2018 | ||
| Mason Highsmith | 152 | 1338.7 | 2017 | ||
| Anthony Godwin | 152 | 1318.3 | 2017 | ||
| Henry Magnan | 152 | 1283.0 | 2017 | ||
| Dicky Kerns | 152 | 1354.7 | 2016 | ||
| Brian Marshall * | 152 | 1337.7 | 2016 | ||
| Mason Highsmith | 152 | 1330.3 | 2016 | ||
| Dicky Kerns | 152 | 1333.7 | 2015 | ||
| Lane Commons * | 152 | 1358.7 | 2014 | ||
| Brian Marshall * | 152 | 1325.7 | 2011 | ||
| Rey Moncayo * | 152 | 1295.3 | 2011 | ||
| Ludwig Claus | 152 | 1313.0 | 2010 | ||
| Mason Highsmith | 152 | 1290.7 | 2010 | ||
| Brian Marshall * | 152 | 1313.0 | 2007 | ||
| Bill Latham | 152 | 1301.3 | 2007 | ||
| Seamus O'Dule * | 152 | 1288.7 | 2006 | ||
| Cyril Foland | 152 | 1259.3 | 2006 | ||
| Humberto Dominguez | 152 | 1281.7 | 2005 | ||
| Zachary Matthews * | 152 | 1272.7 | 2005 | ||
| Danny Rayborn | 152 | 1329.7 | 2001 | ||
| 100. | Tamajirou Kakuzo | 151 | 1302.0 | 2028 |
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