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| Second Basemen Single-Season Slugging Pct Leaderboard | |
| * - Indicates Hall of Fame
+ - indicates hit-less at-bats added to meet 502PA requirement. |
| Rank | Player | Slugging Pct | PA | Year | Career Leaderboard |
| 1. | Summer Nelson * | .5860 | 615 | 2015 | |
| 2. | Summer Nelson * | .5750 | 672 | 2012 | |
| 3. | Blinky Crouch | .5741 | 650 | 2026 | |
| 4. | Seamus O'Dule * | .5691 | 660 | 2010 | |
| 5. | Blinky Crouch | .5614 | 591 | 2021 | |
| 6. | Summer Nelson * | .5512 | 661 | 2011 | |
| 7. | Lane Commons * | .5502 | 628 | 2006 | |
| 8. | Lane Commons * | .5488 | 647 | 2009 | |
| 9. | Adam Anderson | .5453 | 627 | 2010 | |
| 10. | Joel Huertas | .5404 | 729 | 2019 | |
| 11. | Looney Garmendia | .5404 | 680 | 2029 | |
| 12. | Adam Anderson | .5397 | 567 | 2008 | |
| 13. | Summer Nelson * | .5336 | 680 | 2014 | |
| 14. | Rey Moncayo * | .5320 | 644 | 2009 | |
| 15. | Daniel Phillips | .5312 | 647 | 2015 | |
| 16. | Seamus O'Dule * | .5309 | 657 | 2014 | |
| 17. | Seamus O'Dule * | .5296 | 620 | 2005 | |
| 18. | Antonio Ramos | .5295 | 663 | 2000 | |
| 19. | Gary Crawford | .5287 | 686 | 2001 | |
| 20. | Gary Crawford | .5256 | 593 | 2004 | |
| 21. | Summer Nelson * | .5249 | 665 | 2013 | |
| 22. | Adam Anderson | .5236 | 671 | 2006 | |
| 23. | Seamus O'Dule * | .5208 | 630 | 2012 | |
| 24. | Brian Marshall * | .5197 | 662 | 2007 | |
| 25. | Lane Commons * | .5196 | 697 | 2014 | |
| 26. | Lane Commons * | .5191 | 665 | 2007 | |
| 27. | Rey Moncayo * | .5185 | 512 | 2008 | |
| 28. | Brian Marshall * | .5178 | 673 | 2008 | |
| 29. | Lane Commons * | .5176 | 680 | 2016 | |
| 30. | Bob Medforth | .5176 | 654 | 2020 | |
| 31. | Rey Moncayo * | .5149 | 680 | 2011 | |
| 32. | Gary Crawford | .5143 | 562 | 2003 | |
| 33. | John Honeycutt | .5142+ | 500 | 2005 | |
| 34. | Rey Moncayo * | .5118 | 658 | 2013 | |
| 35. | Ludwig Claus | .5106 | 607 | 2009 | |
| 36. | Summer Nelson * | .5092 | 657 | 2007 | |
| 37. | Looney Garmendia | .5091 | 624 | 2028 | |
| 38. | Jack Hesse | .5079 | 704 | 2029 | |
| 39. | Antonio Ramos | .5056 | 710 | 2001 | |
| 40. | Seamus O'Dule * | .5036 | 652 | 2008 | |
| 41. | Seamus O'Dule * | .5036 | 661 | 2013 | |
| 42. | Lane Commons * | .5034 | 682 | 2015 | |
| 43. | Brian Marshall * | .5017 | 667 | 2005 | |
| 44. | Adam Anderson | .5009 | 628 | 2005 | |
| 45. | Gary Crawford | .5009 | 613 | 2005 | |
| 46. | Matthew Wolf | .5000 | 596 | 2026 | |
| 47. | Joel Huertas | .4984 | 703 | 2018 | |
| 48. | Adam Anderson | .4982 | 636 | 2012 | |
| 49. | Brian Marshall * | .4980 | 573 | 2003 | |
| 50. | Summer Nelson * | .4966 | 651 | 2005 | |
| 51. | Rey Moncayo * | .4965 | 673 | 2006 | |
| 52. | Summer Nelson * | .4951 | 677 | 2010 | |
| 53. | Brian Marshall * | .4948 | 637 | 2009 | |
| 54. | William Maxon | .4946 | 702 | 2000 | |
| 55. | Seamus O'Dule * | .4936 | 646 | 2011 | |
| 56. | Antonio Ramos | .4933 | 568 | 2003 | |
| 57. | Daniel Phillips | .4925 | 671 | 2021 | |
| 58. | Ernest Meleschi | .4920 | 626 | 2015 | |
| 59. | Summer Nelson * | .4915 | 660 | 2000 | |
| 60. | Brian Marshall * | .4903 | 671 | 2006 | |
| 61. | Brian Marshall * | .4891 | 644 | 2012 | |
| 62. | Adam Anderson | .4888 | 606 | 2004 | |
| 63. | Rey Moncayo * | .4885 | 678 | 2007 | |
| 64. | Dan Erb | .4877 | 630 | 2017 | |
| 65. | Seamus O'Dule * | .4863 | 662 | 2015 | |
| Antonio Ramos | .4863 | 619 | 2002 | ||
| 67. | Gary Crawford | .4862 | 558 | 2000 | |
| 68. | Bob Medforth | .4861 | 686 | 2019 | |
| 69. | Seamus O'Dule * | .4859 | 616 | 2009 | |
| 70. | Brian Marshall * | .4856 | 628 | 2011 | |
| 71. | Lane Commons * | .4854 | 590 | 2011 | |
| 72. | Bob Medforth | .4851 | 671 | 2022 | |
| 73. | Ludwig Claus | .4847 | 565 | 2007 | |
| 74. | Roger Aker | .4841 | 539 | 2028 | |
| 75. | Cyril Foland | .4829 | 595 | 2008 | |
| 76. | Adam Anderson | .4828 | 618 | 2011 | |
| 77. | Brian Marshall * | .4828 | 617 | 2014 | |
| 78. | Bob Medforth | .4826 | 636 | 2023 | |
| 79. | Seamus O'Dule * | .4823 | 665 | 2004 | |
| 80. | Bobby Whittaker | .4822 | 574 | 2012 | |
| 81. | Jose Abdullah | .4820 | 604 | 2001 | |
| 82. | Bob Medforth | .4818 | 632 | 2018 | |
| 83. | Seamus O'Dule * | .4817 | 582 | 2016 | |
| 84. | Blinky Crouch | .4812 | 653 | 2023 | |
| 85. | Cyril Foland | .4811 | 643 | 2007 | |
| 86. | Andrew Wilson | .4803 | 699 | 2027 | |
| 87. | Seamus O'Dule * | .4802 | 651 | 2006 | |
| 88. | Matthew Wolf | .4793 | 617 | 2024 | |
| 89. | Summer Nelson * | .4791 | 646 | 2016 | |
| 90. | Dan Erb | .4783 | 641 | 2018 | |
| 91. | David Melgoza | .4779 | 582 | 2016 | |
| 92. | Daniel Phillips | .4779 | 630 | 2017 | |
| 93. | Randy McKen | .4772+ | 456 | 2019 | |
| 94. | Rey Moncayo * | .4772 | 637 | 2010 | |
| 95. | Brian Marshall * | .4769 | 647 | 2015 | |
| 96. | Summer Nelson * | .4754 | 651 | 2006 | |
| 97. | Bob Medforth | .4744 | 671 | 2026 | |
| 98. | Howard Luther | .4742 | 610 | 2008 | |
| 99. | Ernest Meleschi | .4742 | 578 | 2012 | |
| 100. | Adam Anderson | .4732 | 679 | 2007 |
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