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| Second Basemen Single-Season Games Started Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Games Started | IP | Year | Career Leaderboard |
| 1. | Todd Maher | 162 | 1441.0 | 2004 | |
| Albert Estrada | 162 | 1448.7 | 2002 | ||
| William Maxon | 162 | 1433.0 | 2001 | ||
| 4. | Joe Berard | 161 | 1444.3 | 2013 | |
| Gary Crawford | 161 | 1445.7 | 2001 | ||
| 6. | Antonio Ramos | 160 | 1416.7 | 2001 | |
| William Maxon | 160 | 1439.3 | 2000 | ||
| Danny Rayborn | 160 | 1435.3 | 2000 | ||
| 9. | Brian Marshall * | 159 | 1426.3 | 2000 | |
| 10. | Eduardo Ulibarri | 157 | 1364.0 | 2014 | |
| Danny Rayborn | 157 | 1321.7 | 2005 | ||
| 12. | Todd Maher | 156 | 1366.3 | 2003 | |
| Frederick Traynor | 156 | 1335.0 | 2001 | ||
| 14. | Josephus Thomas | 155 | 1399.0 | 2006 | |
| Brian Marshall * | 155 | 1407.0 | 2001 | ||
| Zachary Matthews * | 155 | 1361.7 | 2000 | ||
| 17. | Tony Luna | 154 | 1358.3 | 2017 | |
| Joe Berard | 154 | 1401.0 | 2012 | ||
| Joel Camacho | 154 | 1380.0 | 2001 | ||
| 20. | Tamajirou Kakuzo | 153 | 1346.0 | 2029 | |
| Lester Griffey | 153 | 1304.7 | 2023 | ||
| Antonio Ramos | 153 | 1344.7 | 2000 | ||
| Hector Rodriguez | 153 | 1218.3 | 2000 | ||
| 24. | Tamajirou Kakuzo | 152 | 1331.3 | 2017 | |
| Lynn Labrecque | 152 | 1285.7 | 2009 | ||
| Danny Rayborn | 152 | 1318.3 | 2004 | ||
| Zachary Matthews * | 152 | 1359.0 | 2001 | ||
| Matthew Dismukes | 152 | 1310.3 | 2001 | ||
| James Dickson | 152 | 1349.0 | 2000 | ||
| 30. | Bobby Whittaker | 151 | 1344.0 | 2015 | |
| Rex Spikes | 151 | 1338.7 | 2012 | ||
| Danny Rayborn | 151 | 1326.7 | 2007 | ||
| Danny Rayborn | 151 | 1356.7 | 2006 | ||
| Todd Maher | 151 | 1320.3 | 2001 | ||
| Joel Camacho | 151 | 1338.0 | 2000 | ||
| 36. | Leon Nickles | 150 | 1286.7 | 2029 | |
| Bob Medforth | 150 | 1364.0 | 2026 | ||
| Matthew Courtney | 150 | 1303.3 | 2023 | ||
| Anthony Godwin | 150 | 1318.3 | 2017 | ||
| Dicky Kerns | 150 | 1354.7 | 2016 | ||
| Mason Highsmith | 150 | 1329.3 | 2015 | ||
| Brian Marshall * | 150 | 1364.3 | 2008 | ||
| Zachary Matthews * | 150 | 1288.3 | 2002 | ||
| James Dickson | 150 | 1341.0 | 2001 | ||
| Danny Rayborn | 150 | 1329.7 | 2001 | ||
| Hector Rodriguez | 150 | 1158.3 | 2001 | ||
| Jose Abdullah | 150 | 1285.3 | 2000 | ||
| 48. | Jack Hesse | 149 | 1354.7 | 2029 | |
| Jeff Arnette | 149 | 1232.7 | 2029 | ||
| Tamajirou Kakuzo | 149 | 1302.0 | 2028 | ||
| Blinky Crouch | 149 | 1353.3 | 2027 | ||
| Jade Sanchez | 149 | 1313.3 | 2026 | ||
| Anthony Godwin | 149 | 1345.3 | 2024 | ||
| Jeff Arnette | 149 | 1310.3 | 2023 | ||
| Anthony Godwin | 149 | 1338.3 | 2021 | ||
| Henry Magnan | 149 | 1298.7 | 2019 | ||
| Mason Highsmith | 149 | 1338.7 | 2017 | ||
| Lane Commons * | 149 | 1358.7 | 2014 | ||
| Rex Spikes | 149 | 1327.0 | 2013 | ||
| Luis Wooton | 149 | 1248.0 | 2012 | ||
| Joe Hepler | 149 | 1246.3 | 2011 | ||
| Vin Koenig | 149 | 1216.3 | 2009 | ||
| Bill Latham | 149 | 1301.3 | 2007 | ||
| Zachary Matthews * | 149 | 1320.3 | 2003 | ||
| Steven Wynn | 149 | 1285.0 | 2003 | ||
| Frederick Traynor | 149 | 1292.7 | 2002 | ||
| 67. | Jack Hesse | 148 | 1345.0 | 2028 | |
| Bob Medforth | 148 | 1340.7 | 2027 | ||
| Anthony Godwin | 148 | 1310.7 | 2023 | ||
| Daniel Phillips | 148 | 1308.7 | 2023 | ||
| Daniel Phillips | 148 | 1333.0 | 2022 | ||
| August Osvald | 148 | 1304.0 | 2021 | ||
| Henry Magnan | 148 | 1193.0 | 2021 | ||
| Joel Huertas | 148 | 1353.0 | 2019 | ||
| Mason Highsmith | 148 | 1321.7 | 2018 | ||
| Henry Magnan | 148 | 1283.0 | 2017 | ||
| Brian Marshall * | 148 | 1337.7 | 2016 | ||
| Mason Highsmith | 148 | 1330.3 | 2016 | ||
| Brian Marshall * | 148 | 1359.7 | 2013 | ||
| Seamus O'Dule * | 148 | 1331.7 | 2013 | ||
| Luis Wooton | 148 | 1289.3 | 2013 | ||
| Red Rother | 148 | 1297.0 | 2011 | ||
| Seamus O'Dule * | 148 | 1342.0 | 2010 | ||
| Ernest Meleschi | 148 | 1313.3 | 2010 | ||
| Ernest Meleschi | 148 | 1319.0 | 2009 | ||
| Bill Latham | 148 | 1241.3 | 2009 | ||
| Luis Wooton | 148 | 1210.0 | 2009 | ||
| Lane Commons * | 148 | 1350.3 | 2008 | ||
| Robert Wyatt | 148 | 1354.7 | 2004 | ||
| Seamus O'Dule * | 148 | 1351.7 | 2004 | ||
| Danny Rayborn | 148 | 1313.3 | 2003 | ||
| 92. | Issac Phillips | 147 | 1326.3 | 2026 | |
| Jade Sanchez | 147 | 1194.7 | 2025 | ||
| Vin Koenig | 147 | 1264.7 | 2023 | ||
| Vin Koenig | 147 | 1332.0 | 2022 | ||
| Matthew Courtney | 147 | 1265.3 | 2022 | ||
| Tony Luna | 147 | 1263.3 | 2022 | ||
| Seamus O'Dule * | 147 | 1315.3 | 2018 | ||
| David Melgoza | 147 | 1309.7 | 2018 | ||
| David Melgoza | 147 | 1318.7 | 2015 |
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