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| Second Basemen Single-Season On-Base Pct Leaderboard | |
| * - Indicates Hall of Fame
+ - indicates hit-less at-bats added to meet 502PA requirement. |
| Rank | Player | On-Base Pct | PA | Year | Career Leaderboard |
| 1. | Brian Marshall * | .4590 | 573 | 2003 | |
| 2. | Brian Marshall * | .4507 | 671 | 2006 | |
| 3. | Brian Marshall * | .4452 | 757 | 2001 | |
| 4. | Brian Marshall * | .4424 | 651 | 2002 | |
| 5. | Blinky Crouch | .4399 | 591 | 2021 | |
| 6. | Brian Marshall * | .4361 | 667 | 2005 | |
| 7. | Brian Marshall * | .4318 | 762 | 2000 | |
| 8. | Seamus O'Dule * | .4279 | 652 | 2008 | |
| 9. | Seamus O'Dule * | .4270 | 630 | 2012 | |
| 10. | Seamus O'Dule * | .4255 | 665 | 2004 | |
| 11. | Blinky Crouch | .4253 | 663 | 2025 | |
| 12. | Joel Huertas | .4252 | 729 | 2019 | |
| 13. | Looney Garmendia | .4250 | 680 | 2029 | |
| 14. | Seamus O'Dule * | .4245 | 662 | 2015 | |
| 15. | Joel Huertas | .4239 | 703 | 2018 | |
| 16. | Mark Stone | .4226 | 620 | 2025 | |
| 17. | Seamus O'Dule * | .4221 | 661 | 2013 | |
| 18. | Mark Stone | .4210 | 639 | 2026 | |
| 19. | Garry Vandiver | .4198 | 672 | 2028 | |
| 20. | Seamus O'Dule * | .4188+ | 449 | 2017 | |
| 21. | Brian Marshall * | .4184 | 662 | 2007 | |
| 22. | Blinky Crouch | .4182 | 648 | 2024 | |
| 23. | Seamus O'Dule * | .4178 | 651 | 2006 | |
| 24. | Rey Moncayo * | .4148 | 678 | 2007 | |
| 25. | Summer Nelson * | .4145 | 661 | 2011 | |
| 26. | Lane Commons * | .4140 | 628 | 2006 | |
| 27. | Blinky Crouch | .4138 | 650 | 2026 | |
| 28. | Mark Stone | .4123 | 634 | 2028 | |
| 29. | Rey Moncayo * | .4092 | 673 | 2006 | |
| 30. | Seamus O'Dule * | .4084 | 620 | 2005 | |
| 31. | Seamus O'Dule * | .4080+ | 448 | 2007 | |
| 32. | Blinky Crouch | .4080 | 653 | 2023 | |
| 33. | Seamus O'Dule * | .4075 | 616 | 2009 | |
| 34. | Brian Marshall * | .4073 | 659 | 2004 | |
| 35. | Seamus O'Dule * | .4071 | 678 | 2018 | |
| 36. | Seamus O'Dule * | .4064 | 657 | 2014 | |
| 37. | Seamus O'Dule * | .4061 | 660 | 2010 | |
| 38. | Lane Commons * | .4049 | 647 | 2009 | |
| 39. | Mason Highsmith | .4044 | 643 | 2017 | |
| 40. | Mason Highsmith | .4021 | 654 | 2018 | |
| 41. | Blinky Crouch | .4017 | 688 | 2027 | |
| 42. | Mason Highsmith | .4015 | 650 | 2019 | |
| 43. | Rey Moncayo * | .4015 | 687 | 2003 | |
| 44. | Rey Moncayo * | .4012 | 658 | 2013 | |
| 45. | Bates Schatz | .4000 | 580 | 2028 | |
| 46. | Brian Marshall * | .3997 | 673 | 2008 | |
| 47. | Seamus O'Dule * | .3994 | 646 | 2011 | |
| 48. | Mason Highsmith | .3991 | 649 | 2016 | |
| 49. | Anthony Godwin | .3988 | 693 | 2022 | |
| 50. | Seamus O'Dule * | .3986 | 582 | 2016 | |
| 51. | Lane Commons * | .3985 | 680 | 2016 | |
| 52. | Summer Nelson * | .3973 | 672 | 2012 | |
| 53. | Looney Garmendia | .3958 | 624 | 2028 | |
| 54. | Summer Nelson * | .3948 | 651 | 2005 | |
| 55. | Rey Moncayo * | .3944 | 644 | 2009 | |
| 56. | Mark Stone | .3932 | 651 | 2027 | |
| 57. | Lane Commons * | .3931 | 665 | 2007 | |
| 58. | Summer Nelson * | .3929 | 677 | 2010 | |
| 59. | Rey Moncayo * | .3924 | 637 | 2005 | |
| 60. | Garry Vandiver | .3922 | 622 | 2027 | |
| 61. | Summer Nelson * | .3920 | 660 | 2000 | |
| 62. | Andrew Wilson | .3919 | 593 | 2029 | |
| 63. | Rey Moncayo * | .3909 | 637 | 2010 | |
| 64. | Lane Commons * | .3907 | 581 | 2004 | |
| 65. | Mark Stone | .3902 | 512 | 2024 | |
| 66. | Rey Moncayo * | .3897 | 680 | 2011 | |
| 67. | Matthew Wolf | .3890 | 617 | 2028 | |
| 68. | Lane Commons * | .3875 | 640 | 2005 | |
| 69. | Lane Commons * | .3874 | 697 | 2014 | |
| 70. | Mason Highsmith | .3871 | 669 | 2020 | |
| 71. | Joel Huertas | .3867 | 662 | 2021 | |
| 72. | Adam Anderson | .3866 | 628 | 2005 | |
| 73. | Mark Stone | .3865+ | 494 | 2021 | |
| 74. | Rey Moncayo * | .3860 | 686 | 2004 | |
| 75. | Dude Gallagher | .3849 | 652 | 2023 | |
| 76. | Lane Commons * | .3848 | 512 | 2012 | |
| 77. | Lane Commons * | .3842 | 682 | 2015 | |
| 78. | Summer Nelson * | .3838 | 628 | 2009 | |
| 79. | Garry Vandiver | .3831+ | 469 | 2029 | |
| 80. | Lane Commons * | .3831 | 590 | 2011 | |
| 81. | Blinky Crouch | .3829 | 598 | 2028 | |
| 82. | Lane Commons * | .3823 | 633 | 2017 | |
| 83. | Bob Medforth | .3823 | 654 | 2020 | |
| 84. | Summer Nelson * | .3821 | 615 | 2015 | |
| 85. | Brian Marshall * | .3820 | 644 | 2012 | |
| 86. | Mark Stone | .3817 | 634 | 2029 | |
| 87. | Summer Nelson * | .3809 | 680 | 2014 | |
| 88. | Lane Commons * | .3809 | 659 | 2008 | |
| 89. | Rey Moncayo * | .3809 | 512 | 2008 | |
| 90. | Anthony Godwin | .3803 | 660 | 2024 | |
| 91. | Adam Anderson | .3795 | 606 | 2004 | |
| 92. | Adam Anderson | .3792 | 567 | 2008 | |
| 93. | Daniel Phillips | .3792 | 662 | 2022 | |
| 94. | Garry Vandiver | .3791 | 546 | 2026 | |
| 95. | Adam Anderson | .3787 | 671 | 2006 | |
| 96. | Blinky Crouch | .3783 | 600 | 2029 | |
| 97. | Daniel Phillips | .3770 | 671 | 2021 | |
| 98. | Bates Schatz | .3764 | 619 | 2029 | |
| 99. | Joel Huertas | .3761 | 686 | 2017 | |
| 100. | Joel Huertas | .3757 | 684 | 2022 |
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