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| Second Basemen Career OPS Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | OPS | PA | Years | Single Season Leaderboard |
| 1. | Seamus O'Dule * | .8940 | 11331 | 2002-2021 | |
| 2. | Blinky Crouch | .8651 | 6751 | 2018-2029 | |
| 3. | Lane Commons * | .8609 | 9290 | 2003-2017 | |
| 4. | Summer Nelson * | .8589 | 13326 | 2000-2020 | |
| 5. | Rey Moncayo * | .8515 | 7698 | 2002-2014 | |
| 6. | Brian Marshall * | .8325 | 12282 | 2000-2018 | |
| 7. | Andrew Wilson | .8200 | 3737 | 2024-2029 | |
| 8. | Adam Anderson | .8171 | 8316 | 2001-2016 | |
| 9. | Joel Huertas | .7967 | 10198 | 2014-2029 | |
| 10. | Bates Schatz | .7865 | 3542 | 2024-2029 | |
| 11. | Mark Stone | .7861 | 5743 | 2018-2029 | |
| 12. | Bob Medforth | .7808 | 6924 | 2018-2029 | |
| 13. | Daniel Phillips | .7725 | 9012 | 2014-2028 | |
| 14. | Joseph Flores | .7676 | 5516 | 2019-2029 | |
| 15. | Antonio Ramos | .7630 | 4081 | 2000-2008 | |
| 16. | Matthew Wolf | .7580 | 8475 | 2015-2029 | |
| 17. | Mason Highsmith | .7559 | 10686 | 2007-2024 | |
| 18. | Anthony Godwin | .7551 | 8267 | 2015-2029 | |
| 19. | Ernest Meleschi | .7548 | 6493 | 2007-2019 | |
| 20. | Gary Crawford | .7532 | 5657 | 2000-2009 | |
| 21. | Oscar Nolan | .7510 | 5379 | 2019-2029 | |
| 22. | John Honeycutt | .7496 | 3832 | 2003-2013 | |
| 23. | Todd Castiglia | .7495 | 5873 | 2000-2016 | |
| 24. | Garry Vandiver | .7450 | 4892 | 2020-2029 | |
| 25. | Fernando Selso | .7442 | 3300 | 2024-2029 | |
| 26. | Ludwig Claus | .7409 | 7196 | 2005-2022 | |
| 27. | Jeff Arnette | .7398 | 4967 | 2021-2029 | |
| 28. | David Melgoza | .7361 | 5545 | 2010-2023 | |
| 29. | Rene Searles | .7336 | 7383 | 2011-2025 | |
| 30. | Bobby Whittaker | .7329 | 6765 | 2010-2026 | |
| 31. | Howard Luther | .7292 | 5332 | 2003-2014 | |
| 32. | Vin Koenig | .7280 | 9411 | 2007-2023 | |
| 33. | Cyril Foland | .7228 | 5514 | 2003-2013 | |
| 34. | Dan Erb | .7205 | 7384 | 2009-2021 | |
| 35. | Ed Parker | .7202 | 3232 | 2022-2029 | |
| 36. | Jim Masson | .7197 | 4093 | 2016-2029 | |
| 37. | William Maxon | .7197 | 4637 | 2000-2008 | |
| 38. | Red Rother | .7100 | 4625 | 2009-2018 | |
| 39. | Jesus Tabares | .7058 | 3372 | 2022-2029 | |
| 40. | Dave Dancey | .7054 | 4834 | 2020-2029 | |
| 41. | Todd Maher | .7021 | 4549 | 2000-2008 | |
| 42. | Frederick Traynor | .7012 | 3482 | 2000-2006 | |
| 43. | Humberto Dominguez | .6994 | 3531 | 2000-2011 | |
| 44. | Joel Camacho | .6952 | 3453 | 2000-2005 | |
| 45. | Danny Rayborn | .6942 | 5328 | 2000-2008 | |
| 46. | Adrian Turgeon | .6886 | 3187 | 2017-2029 | |
| 47. | James Dickson | .6868 | 3717 | 2000-2009 | |
| 48. | Randy McKen | .6851 | 3078 | 2012-2022 | |
| 49. | Bruce Howes | .6837 | 4009 | 2001-2014 | |
| 50. | Henry Davis | .6820 | 6413 | 2005-2020 | |
| 51. | Joe Hepler | .6813 | 4874 | 2006-2016 | |
| 52. | Zachary Matthews * | .6809 | 7672 | 2000-2012 | |
| 53. | Jake Kinchen | .6785 | 4878 | 2017-2029 | |
| 54. | Joseph Sharkey | .6772 | 3257 | 2000-2005 | |
| 55. | Dude Gallagher | .6736 | 3298 | 2019-2029 | |
| 56. | David Cimino | .6720 | 3000 | 2009-2020 | |
| 57. | Tamajirou Kakuzo | .6696 | 7146 | 2015-2029 | |
| 58. | Brett Eisen | .6679 | 3050 | 2000-2011 | |
| 59. | Harvey Thornton | .6671 | 5456 | 2016-2029 | |
| 60. | Eugene Hove | .6661 | 3776 | 2007-2017 | |
| 61. | Manuel Rodriguez | .6646 | 6614 | 2007-2019 | |
| 62. | Arron Silvia | .6641 | 3452 | 2005-2013 | |
| 63. | Allen Lively | .6617 | 6045 | 2011-2022 | |
| 64. | Darius Mosqueda | .6526 | 4124 | 2000-2011 | |
| 65. | Abe Seemann | .6438 | 5043 | 2005-2017 | |
| 66. | George Mingham | .6408 | 3211 | 2010-2023 | |
| 67. | James Erickson | .6341 | 4383 | 2005-2020 | |
| 68. | Henry Magnan | .6331 | 6019 | 2014-2027 | |
| 69. | David Reddaway | .6319 | 5023 | 2019-2029 | |
| 70. | Bill Latham | .6196 | 4352 | 2007-2014 | |
| 71. | Joshua Sidwell | .6090 | 5209 | 2014-2024 | |
| 72. | Samuel Warlick | .5953 | 4031 | 2001-2016 | |
| 73. | Josephus Thomas | .5778 | 5782 | 2004-2016 |
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