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| Center Fielders Career RBIs Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | RBIs | PA | Years | Single Season Leaderboard |
| 1. | Harold Petrillo * | 1383 | 8516 | 2003-2019 | |
| 2. | J.D. Arney | 1349 | 9609 | 2003-2018 | |
| 3. | Blair Payton | 1238 | 10362 | 2012-2029 | |
| 4. | Sylvester Suarez | 1130 | 7271 | 2014-2028 | |
| 5. | Cliff Butter | 1088 | 6965 | 2017-2029 | |
| 6. | Steven Huggan | 1084 | 9505 | 2006-2022 | |
| 7. | Armando Mesa | 1060 | 6656 | 2000-2010 | |
| 8. | Leo Brailsford | 1048 | 8379 | 2011-2026 | |
| 9. | Floyd Perreira | 1013 | 8353 | 2005-2020 | |
| 10. | Delmar Barrie | 958 | 10082 | 2007-2025 | |
| 11. | Bobby Nuņo | 940 | 6736 | 2011-2025 | |
| 12. | Jay Trotter | 937 | 7536 | 2014-2029 | |
| 13. | Bill Newbold | 928 | 6756 | 2019-2029 | |
| 14. | Andy Ping | 909 | 5678 | 2021-2029 | |
| 15. | Karl Immell | 905 | 9774 | 2011-2027 | |
| 16. | Christopher Cortese | 900 | 5951 | 2000-2010 | |
| 17. | Grady Client | 872 | 8604 | 2011-2027 | |
| 18. | Alex Garza * | 850 | 6820 | 2000-2011 | |
| 19. | Francisco Diaz | 838 | 7844 | 2006-2021 | |
| 20. | Thomas Holtzclaw | 809 | 5446 | 2000-2009 | |
| 21. | Roy Lininger | 793 | 6785 | 2005-2017 | |
| 22. | Kelvin Varga | 728 | 5140 | 2000-2008 | |
| 23. | Tom Galaxy | 723 | 6355 | 2019-2029 | |
| 24. | Franklyn Thom | 715 | 6297 | 2008-2021 | |
| 25. | Eric Fender | 700 | 5189 | 2020-2029 | |
| 26. | Lee Desilva | 687 | 5741 | 2020-2029 | |
| 27. | Blair Glaspie | 684 | 5234 | 2021-2029 | |
| 28. | Greg Holt | 649 | 4916 | 2021-2029 | |
| Joe Wilson | 649 | 5255 | 2012-2021 | ||
| 30. | Josh Kapaun | 637 | 4800 | 2000-2007 | |
| 31. | Antony Kissel | 586 | 4347 | 2000-2011 | |
| 32. | Ronnie Brito | 582 | 7281 | 2000-2011 | |
| 33. | Adrian Ahmad | 580 | 6434 | 2000-2011 | |
| 34. | Dante Holleman | 551 | 4289 | 2001-2012 | |
| 35. | John Kubisiak | 547 | 5710 | 2005-2017 | |
| 36. | Eric Wheeler | 546 | 5482 | 2003-2013 | |
| 37. | Christopher Radford | 538 | 5162 | 2003-2013 | |
| Jose Romriell | 538 | 6377 | 2000-2009 | ||
| 39. | Paul Thomas | 505 | 6042 | 2008-2019 | |
| 40. | Alfonso Camino | 486 | 5251 | 2021-2029 | |
| 41. | Lawrence Noel | 473 | 4331 | 2000-2011 | |
| 42. | Domingo Nuno | 453 | 3962 | 2019-2029 | |
| 43. | Kevin Moorhead | 431 | 4091 | 2002-2012 | |
| 44. | Sledgehammer Neff | 426 | 4429 | 2022-2029 | |
| Glen Mallory | 426 | 3401 | 2024-2029 | ||
| Tony Bergeron | 426 | 4383 | 2004-2015 | ||
| 47. | Jeff McGwire | 423 | 3897 | 2019-2028 | |
| 48. | James Lape | 415 | 4193 | 2005-2017 | |
| 49. | Michael Walsh | 414 | 3836 | 2011-2023 | |
| 50. | Bobby Karn | 408 | 3339 | 2000-2010 | |
| 51. | Aluino Castellan | 407 | 4177 | 2022-2029 | |
| 52. | Eugene Grimes | 404 | 4220 | 2021-2029 | |
| 53. | Gil Cushingham | 389 | 4083 | 2023-2029 | |
| Wally Brinklow | 389 | 2716 | 2025-2029 | ||
| 55. | Dale Couch | 363 | 1918 | 2026-2029 | |
| 56. | Norman Davis | 360 | 3714 | 2015-2023 | |
| 57. | Michael Koo Iii | 359 | 2848 | 2022-2029 | |
| Joseph Simons | 359 | 3488 | 2004-2014 | ||
| 59. | Maruice Rapko | 348 | 3668 | 2014-2022 | |
| 60. | Lawrence Garney | 340 | 4089 | 2015-2029 | |
| 61. | Ken Waddell | 336 | 2944 | 2020-2029 | |
| 62. | Milt Kovac | 335 | 3525 | 2006-2015 | |
| 63. | Robert Kent | 327 | 3181 | 2024-2029 | |
| 64. | Edward Klein | 325 | 2964 | 2017-2029 | |
| Oscar Fetters | 325 | 3568 | 2000-2012 | ||
| Nicholas Deroche | 325 | 3226 | 2000-2007 | ||
| 67. | Victor Olin | 317 | 3540 | 2003-2016 | |
| 68. | John Ross | 274 | 2871 | 2000-2005 | |
| 69. | Aaron Lietz | 271 | 3351 | 2000-2009 | |
| 70. | Rosendo Centeno | 269 | 3041 | 2000-2010 | |
| 71. | Zack Russell | 266 | 2360 | 2023-2029 | |
| 72. | Michael Miller | 256 | 2605 | 2000-2007 | |
| 73. | Marcus Gavardo | 255 | 2569 | 2024-2029 | |
| 74. | David Seagate | 254 | 1919 | 2027-2029 | |
| 75. | John Pigeon | 249 | 3100 | 2021-2029 | |
| Glenn Procter | 249 | 2455 | 2026-2029 | ||
| 77. | Alton Torres | 246 | 2385 | 2000-2007 | |
| 78. | Jason Lawrence | 240 | 2368 | 2000-2004 | |
| 79. | Ramon Puente | 238 | 2689 | 2008-2019 | |
| 80. | Benny Powell | 232 | 2234 | 2013-2021 | |
| 81. | Shane Dollar | 231 | 2071 | 2021-2029 | |
| 82. | John Charity | 224 | 2814 | 2002-2012 | |
| 83. | Pedro Sancho | 223 | 2094 | 2000-2009 | |
| 84. | Leo Blatt | 222 | 2504 | 2000-2004 | |
| 85. | Jose Calles | 215 | 2876 | 2005-2013 | |
| 86. | Carlos Contoeras | 209 | 1771 | 2021-2029 | |
| Thomas Locklin | 209 | 2448 | 2014-2022 | ||
| 88. | Angel Allen | 203 | 2287 | 2011-2019 | |
| 89. | Amos Colburn | 201 | 1929 | 2001-2014 | |
| 90. | Anthony Gibson | 194 | 2243 | 2025-2029 | |
| Jack Gallucci | 194 | 2415 | 2006-2016 | ||
| 92. | Ahmed Thompson | 193 | 1723 | 2000-2004 | |
| 93. | Gregorio Mateo | 191 | 1767 | 2000-2010 | |
| 94. | John Livesay | 180 | 1399 | 2001-2011 | |
| 95. | Amadeo Barrea | 178 | 1634 | 2022-2029 | |
| 96. | Aaron Davis | 174 | 1971 | 2027-2029 | |
| 97. | Marcellus Antunez | 166 | 1720 | 2004-2013 | |
| Alex Loaiza | 166 | 1462 | 2000-2005 | ||
| 99. | Jeffrey Clow | 162 | 2064 | 2001-2008 | |
| 100. | Jose Baez | 154 | 1010 | 2028-2029 |
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