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| First Basemen Single-Season Innings Played Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Innings Played | IP | Year | Career Leaderboard |
| 1. | Jarvis Holeman | 1490.3 | 1490.3 | 2014 | |
| 2. | Howard Lovecraft | 1476.3 | 1476.3 | 2017 | |
| 3. | Steve McLaughlin | 1474.7 | 1474.7 | 2016 | |
| 4. | Antonio Herrera | 1474.3 | 1474.3 | 2011 | |
| 5. | Ed Abrams | 1463.3 | 1463.3 | 2026 | |
| 6. | Nobukazu Takemura | 1462.3 | 1462.3 | 2004 | |
| 7. | James Schlemmer | 1460.3 | 1460.3 | 2024 | |
| 8. | Antonio Herrera | 1458.0 | 1458.0 | 2009 | |
| 9. | Nobukazu Takemura | 1451.3 | 1451.3 | 2005 | |
| 10. | Antonio Herrera | 1450.3 | 1450.3 | 2012 | |
| 11. | Hal Rehm | 1448.3 | 1448.3 | 2019 | |
| 12. | Jarvis Holeman | 1447.7 | 1447.7 | 2011 | |
| 13. | Ed Abrams | 1443.0 | 1443.0 | 2025 | |
| Jarvis Holeman | 1443.0 | 1443.0 | 2013 | ||
| Antonio Herrera | 1443.0 | 1443.0 | 2010 | ||
| 16. | James Roselli | 1435.7 | 1435.7 | 2001 | |
| 17. | Winston Pearl | 1433.0 | 1433.0 | 2023 | |
| 18. | Ron Brenton | 1428.3 | 1428.3 | 2001 | |
| 19. | Ron Brenton | 1423.0 | 1423.0 | 2000 | |
| 20. | Hal Rehm | 1422.0 | 1422.0 | 2013 | |
| 21. | Jonas Diaz | 1419.7 | 1419.7 | 2017 | |
| 22. | Jimmie Davis * | 1418.0 | 1418.0 | 2000 | |
| 23. | Jimmie Davis * | 1414.3 | 1414.3 | 2001 | |
| 24. | Renaldo Loera | 1411.0 | 1411.0 | 2001 | |
| 25. | Mohammed Cardenas | 1402.0 | 1402.0 | 2000 | |
| 26. | Terrance Minor | 1401.0 | 1401.0 | 2001 | |
| 27. | Tyler Utah | 1400.7 | 1400.7 | 2001 | |
| 28. | Hugo Grimm | 1395.0 | 1395.0 | 2001 | |
| 29. | Steve McLaughlin | 1390.7 | 1390.7 | 2017 | |
| 30. | Felix Atkinson | 1384.7 | 1384.7 | 2001 | |
| 31. | James Schlemmer | 1382.7 | 1382.7 | 2022 | |
| 32. | Steve McLaughlin | 1382.0 | 1382.0 | 2019 | |
| 33. | Hugo Grimm | 1380.3 | 1380.3 | 2000 | |
| 34. | Hal Rehm | 1379.0 | 1379.0 | 2011 | |
| 35. | Terrance Minor | 1378.7 | 1378.7 | 2000 | |
| 36. | Adolph Egerton | 1378.0 | 1378.0 | 2027 | |
| 37. | Curtis Kulp | 1373.7 | 1373.7 | 2023 | |
| 38. | Earl Lewis | 1373.3 | 1373.3 | 2026 | |
| 39. | Paul Sidgwick | 1372.7 | 1372.7 | 2023 | |
| 40. | Renaldo Loera | 1371.3 | 1371.3 | 2000 | |
| 41. | Winston Pearl | 1370.7 | 1370.7 | 2022 | |
| 42. | Jarvis Holeman | 1370.3 | 1370.3 | 2012 | |
| 43. | Jerry Rivers | 1369.3 | 1369.3 | 2022 | |
| 44. | Richard Willie | 1367.7 | 1367.7 | 2000 | |
| 45. | Hal Rehm | 1366.7 | 1366.7 | 2018 | |
| 46. | Hal Rehm | 1364.3 | 1364.3 | 2010 | |
| 47. | Tyler Utah | 1363.3 | 1363.3 | 2000 | |
| 48. | Dean Chalmers | 1358.3 | 1358.3 | 2016 | |
| 49. | Jerry Rivers | 1356.7 | 1356.7 | 2017 | |
| 50. | David Occhipinti | 1356.3 | 1356.3 | 2024 | |
| 51. | Paul Sidgwick | 1355.3 | 1355.3 | 2025 | |
| 52. | Rafael Delrosario | 1353.7 | 1353.7 | 2014 | |
| 53. | Hank Carruthers | 1353.3 | 1353.3 | 2027 | |
| 54. | Carl Wesolowski | 1353.0 | 1353.0 | 2007 | |
| Albert Ortega | 1353.0 | 1353.0 | 2004 | ||
| 56. | Cole Watterson | 1352.3 | 1352.3 | 2024 | |
| 57. | Paul Sidgwick | 1350.7 | 1350.7 | 2028 | |
| 58. | Luis Rodriguez | 1349.7 | 1349.7 | 2029 | |
| Hank Carruthers | 1349.7 | 1349.7 | 2026 | ||
| 60. | Nobukazu Takemura | 1348.7 | 1348.7 | 2014 | |
| 61. | Ben Perez | 1348.0 | 1348.0 | 2004 | |
| 62. | Dan Staub | 1347.3 | 1347.3 | 2014 | |
| 63. | John Gleaves | 1346.7 | 1346.7 | 2014 | |
| Graham Brown | 1346.7 | 1346.7 | 2001 | ||
| 65. | Howard Lovecraft | 1346.3 | 1346.3 | 2016 | |
| 66. | Michael Cadiz | 1345.0 | 1345.0 | 2029 | |
| 67. | James Roselli | 1344.7 | 1344.7 | 2004 | |
| 68. | Nightmare Massengill | 1344.3 | 1344.3 | 2025 | |
| Chet Rinehart | 1344.3 | 1344.3 | 2006 | ||
| Leon Brouwer | 1344.3 | 1344.3 | 2005 | ||
| 71. | Mack Outlaw | 1343.7 | 1343.7 | 2027 | |
| 72. | Carl Wesolowski | 1342.7 | 1342.7 | 2008 | |
| 73. | Hal Rehm | 1342.3 | 1342.3 | 2020 | |
| 74. | Graham Brown | 1342.0 | 1342.0 | 2000 | |
| 75. | Nobukazu Takemura | 1341.3 | 1341.3 | 2010 | |
| 76. | Jacks Nito | 1341.0 | 1341.0 | 2016 | |
| 77. | Dean Chalmers | 1339.3 | 1339.3 | 2015 | |
| 78. | Donald Birnbaum | 1339.0 | 1339.0 | 2007 | |
| 79. | Thad Hambro | 1338.0 | 1338.0 | 2029 | |
| 80. | Jacks Nito | 1337.7 | 1337.7 | 2015 | |
| 81. | John Ransom | 1336.7 | 1336.7 | 2022 | |
| John Ransom | 1336.7 | 1336.7 | 2016 | ||
| 83. | Renaldo Loera | 1336.0 | 1336.0 | 2005 | |
| 84. | John Ransom | 1335.3 | 1335.3 | 2019 | |
| Hal Rehm | 1335.3 | 1335.3 | 2014 | ||
| Renaldo Loera | 1335.3 | 1335.3 | 2002 | ||
| 87. | Scott Davis | 1335.0 | 1335.0 | 2027 | |
| 88. | James Schlemmer | 1334.7 | 1334.7 | 2021 | |
| 89. | Jacks Nito | 1334.0 | 1334.0 | 2017 | |
| 90. | Antonio Herrera | 1333.3 | 1333.3 | 2000 | |
| 91. | John Gleaves | 1333.0 | 1333.0 | 2015 | |
| 92. | Felix Atkinson | 1332.7 | 1332.7 | 2003 | |
| Richard Willie | 1332.7 | 1332.7 | 2001 | ||
| 94. | Hal Rehm | 1332.0 | 1332.0 | 2016 | |
| 95. | Tyrell Silvera Jr | 1331.7 | 1331.7 | 2024 | |
| Denver Robinson | 1331.7 | 1331.7 | 2021 | ||
| 97. | Johnny Carmona | 1331.0 | 1331.0 | 2014 | |
| 98. | Edward Klein | 1330.0 | 1330.0 | 2028 | |
| Renaldo Loera | 1330.0 | 1330.0 | 2004 | ||
| 100. | Paul Sidgwick | 1329.7 | 1329.7 | 2026 |
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